- Di processo
- An immune-mediated etiology is advocated in which the cns is hit by
different pathogen-driven (auto)immune responses. A dimensional view,
taking into account the multifactorial origin of psychiatric disorders,
should suggest neuro-inflammation as a possible shared substrate of
different psychiatric phenotypes. The conference starts presenting the
inflammatory hypothesis and its mechanism (E.G. The microglial
activation; the hyperpermeability of bbb, etc).
- Professionali
- Pediatric acute-onset neuropsychiatric syndrome (pans) features a
heterogeneous constellation of acute obsessive-compulsive disorder
(ocd), eating restriction, cognitive, behavioral and/or affective
symptoms, often followed by a chronic course with cognitive
deterioration
- Di sistema
- The second part is focused on pans and discusses the clinical (ie,
diagnostic criteria, pre-existing neurodevelopmental disorders,
neuroimaging), pathophysiological (ie, csf, serum, genetic and
autoimmune findings) and therapeutic (immunomodulation/antiinflammatory
and antibiotics treatments in association with both
psychotropic and cognitive-behavioral therapies) aspects of the